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Cytotec (Misoprostol) is used to prevent stomach ulcers while you take NSAIDs (e.g., aspirin, ibuprofen, naproxen).

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Drug Name

Cytotec (Misoprostol)

Drug Uses

This medication is used to prevent stomach ulcers while you take NSAIDs (e.g., aspirin, ibuprofen, naproxen), especially if you are at risk for developing ulcers or have a history of ulcers. Cytotec helps to decrease your risk of serious ulcer complications such as bleeding. This medication protects your stomach lining by lowering the amount of acid that comes in contact with it. This medication is also used in combination with another drug (mifepristone) to end a pregnancy (abortion).

How Taken

This medicine comes with a patient information leaflet. Read it carefully. If you have any questions about this drug, ask your doctor, nurse, or pharmacist. Dosage is based on your medical condition and response to therapy. If you are taking this drug to prevent stomach ulcers, take it by mouth usually four times a day, after meals and at bedtime to minimize diarrhea, or as directed by your doctor. If you are taking this medication for abortion, take it by mouth exactly as directed by your doctor. If you are using this medication to start labor, your healthcare professional will insert it into your vagina. Avoid taking antacids that contain magnesium while using cytotec because they may make the diarrhea it causes worse. If you need an antacid, consult your doctor or pharmacist to help you choose a product. For ulcer prevention, continue to take this drug for as long as you take NSAIDs. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. Inform your doctor if your condition persists or worsens.

Drug Class and Mechanism

Cytotec is a synthetic prostaglandin. Prostaglandins are natural substances found in the stomach as well as in other organs of the human body. In the stomach, prostaglandins are believed to protect the inner stomach lining from the ulcer-producing effects of acid, aspirin, and other nonsteroidal anti-inflammatory drugs (NSAIDs), commonly used in the treatment of arthritis and other inflammatory conditions. Scientists now believe that aspirin and NSAIDs produce stomach ulceration mostly by inhibiting the production of prostaglandins in the stomach. Synthetic prostaglandin such as cytotec, given orally, has been shown to protect the stomach lining from ulcerating effects of NSAIDs.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at or below 77 degrees F (25 degrees C) in a dry place away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

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