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Coreg (Carvedilol) is used to treat high blood pressure and heart failure.

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Drug Name

Coreg (Carvedilol)

Drug Uses

This medication is an alpha- and beta-blocker, used to treat high blood pressure and heart failure. It is also used after an acute heart attack to improve survival. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems. This drug works by blocking the action of certain natural chemicals in your body (such as epinephrine) that affect the heart and blood vessels. This results in lowering of heart rate, blood pressure, and strain on the heart.

How Taken

Take this medication by mouth with food, usually twice daily, or as directed by your doctor. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. Take this drug exactly as prescribed. Do not increase or decrease the dose on your own. The dosage is based on your medical condition and response to therapy. If you are being treated for high blood pressure, it may take 1 or 2 weeks before the full benefit of this drug takes effect. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. Do not suddenly stop taking this medication without consulting your doctor. Your condition may become worse when the drug is suddenly stopped.

Drug Class and Mechanism

Coreg is used for treating high blood pressure and congestive heart failure. It is related to labetalol (Normodyne, Trandate). Coreg blocks receptors of the adrenergic nervous system, the system of nerves in which epinephrine (adrenalin) is active. Nerves from the adrenergic system enter the heart and release an adrenergic chemical (norepinephrine) that attaches to receptors on the heart's muscle and stimulates the muscle to beat more rapidly and forcefully. By blocking the receptors, coreg reduces the heart's rate and force of contraction and, thereby, reduces the work of the heart. Coreg also blocks adrenergic receptors on arteries and causes the arteries to relax and the blood pressure to fall. The drop in blood pressure further reduces the work of the heart since it is easier to pump blood against a lower pressure.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature below 86 degrees F (30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

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